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European Space Agency (ESA) staff are planning future research into the possibility of inducing a hibernation-like state in humans.ESA believes hibernation would help astronauts to cope with the psychological demands of decades-long return journeys to destinations such as Saturn. And because less space and food would be needed on such missions, the spacecraft would be lighter and easier to launch.
Inquiry centres on DADLE (D-Ala,D-Leu-enkephalin), a substance with opium-like properties. An injection of DADLE is known to trigger hibernation in ground squirrels during the summer season, when the animals would normally be awake. It also seems to send cultures of human cells to sleep: the cells divide more slowly and their gene activity drops when the molecule is applied.
Researchers are following up other leads too. One downside of hibernation is that it leads to loss of muscle strength, a problem that also afflicts patients confined to bed after an operation. Such bedridden patients retain more strength if they receive dobutamine, a drug used to boost the strength of heart muscles, so a similar treatment might work during hibernation.
But practical hibernation mechanisms are at least a decade away.

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